{"id":4586,"date":"2024-12-23T20:05:55","date_gmt":"2024-12-23T20:05:55","guid":{"rendered":"https:\/\/macumira-premium.4ecps.com\/?p=4203"},"modified":"2025-08-20T21:06:14","modified_gmt":"2025-08-20T21:06:14","slug":"age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd","status":"publish","type":"post","link":"https:\/\/macumira.com\/ca\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/","title":{"rendered":"Age-related macular degeneration (AMD) doesn\u2019t always progress to wet AMD"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Good news for those with AMD: only about 10 per cent of cases progress from the less severe dry form to the more serious wet form, which poses greater risks to vision.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Here\u2019s how to reduce your risk\u2026<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How AMD affects the retina and macula<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/macumira.com\/about-amd\/\" target=\"_blank\" rel=\"noreferrer noopener\">Age-related macular degeneration (AMD)<\/a>&nbsp;is a progressive eye disease wherein the part of the retina called the macula is damaged.<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn1\"><sup>[1]<\/sup><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cAMD affects the central part of the retina, an area called the macula, hence the name,\u201d explains Dr. Flavio Rezende, a vitreo retinologist at the Maisonneuve-Rosemont Hospital\u2019s University Ophthalmology Centre and a Professor of Ophthalmology at the University of Montreal. \u201cThe disease is an abnormal aging of cells called photoreceptors, which capture the light that goes into the eye and transform it into messaging to the brain.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These photoreceptors are found in the centralmost region of the macula, the foveola.<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn1\"><sup>[2]<\/sup><\/a>&nbsp;This part of the eye, and the macula in general, is responsible for the detailed vision necessary for activities such as reading, driving and recognizing people\u2019s faces.<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn2\"><sup>[3]<\/sup><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><noscript><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/macumira.com\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1024x683.jpg\" alt class=\"wp-image-4893\" srcset=\"https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1024x683.jpg 1024w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-300x200.jpg 300w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-768x512.jpg 768w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1536x1024.jpg 1536w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-2048x1365.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\"><\/noscript><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201024%20683%22%3E%3C%2Fsvg%3E\" alt class=\"wp-image-4893 lazyload\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201024%20683%22%3E%3C%2Fsvg%3E 1024w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" data-srcset=\"https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1024x683.jpg 1024w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-300x200.jpg 300w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-768x512.jpg 768w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1536x1024.jpg 1536w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-2048x1365.jpg 2048w\" data-src=\"https:\/\/macumira.com\/wp-content\/uploads\/sites\/3\/2025\/07\/Dry-AMD-to-Wet-AMD-1024x683.jpg\"><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">The Warning Signs: Drusen and Early Indicators of AMD<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">As the name suggests, AMD develops as the eyes age. \u201cWe need vision every minute that we\u2019re awake, so these tissues have to work hard every day,\u201d says Dr. Rezende. \u201cThe mix of light and oxygen creates waste products called free radicals, which start to accumulate over the years, and this can eventually damage the cells.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Early signs of this accumulation of waste products include drusen \u2013 deposits of lipids and proteins under the retina.<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn1\"><sup>[4]<\/sup><\/a>&nbsp;Having drusen is a hallmark of AMD,<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn2\"><sup>[4]<\/sup><\/a>&nbsp;says Dr. Rezende.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftnref1\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftnref1\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Drusen alone does not account for a AMD diagnosis, but it is, however, a warning sign. Over time, patients with drusen can be more or less likely to advance into AMD depending on a variety of factors, including genetics and lifestyle. Patients who develop AMD may get either or both of its two forms: dry AMD and wet AMD.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cAs you advance, you can go into the dry form of AMD, which is usually the natural history of the disease, or the wet form, which happens in about 10 per cent of patients,\u201d says Dr. Rezende. \u201cDry AMD is the accumulation of drusen. The cells eventually stop functioning \u2013 they become atrophic and pretty much die. In some patients, however, before the cells die, they create a stimulus to try to attract new blood vessels toward them, which we call new vascularization, and this is the wet form of AMD. The new vessels don\u2019t have the same capacity as regular blood vessels to keep the blood inside the vessels, so they start leaking, and that\u2019s why we call it the wet form.\u201d<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn1\"><sup>[5]<\/sup><\/a><br><br>As mentioned, wet AMD is far more serious than the dry version. \u201cWhen you develop the wet form, there\u2019s a quick drop in vision,\u201d says Dr. Rezende. \u201cAll of a sudden you may have a dark spot in the central part of your visual field, which will impact reading and recognizing faces, and you may also have colour deficiencies. It\u2019s a very debilitating disease.\u201d By contrast, dry AMD usually involves slow-progressing vision impairment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Wet AMD is also associated with a significant treatment burden. \u201cThe treatment consists of an eye injection every four to sixteen weeks,\u201d notes Dr. Rezende.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><noscript><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/macumira.com\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1.jpg\" alt class=\"wp-image-4894\" srcset=\"https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1.jpg 1024w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1-300x200.jpg 300w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1-768x512.jpg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\"><\/noscript><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201024%20683%22%3E%3C%2Fsvg%3E\" alt class=\"wp-image-4894 lazyload\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201024%20683%22%3E%3C%2Fsvg%3E 1024w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" data-srcset=\"https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1.jpg 1024w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1-300x200.jpg 300w, https:\/\/macumira.com\/ca\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1-768x512.jpg 768w\" data-src=\"https:\/\/macumira.com\/wp-content\/uploads\/sites\/3\/2025\/07\/Wet-AMD-Treatment-1024x683-1.jpg\"><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">MacuMira Vision Therapy for Dry AMD treatment<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Those diagnosed with dry AMD, however,&nbsp;<a href=\"https:\/\/macumira.com\/treatment-for-amd\/\" target=\"_blank\" rel=\"noreferrer noopener\">can be treated with MacuMira Vision Therapy<\/a>&nbsp;which is far more comfortable, and clinically effective, than many of the existing traditional therapies. MacuMira Vision Therapy uses&nbsp;<a href=\"https:\/\/macumira.com\/product-therapy-overview\/\" target=\"_blank\" rel=\"noreferrer noopener\">non-invasive eyelid surface neurostimulation<\/a>&nbsp;to deliver a patented microcurrent through a patient\u2019s closed eyes. This is a quick and easy process that improves visual acuity by an average of 8.8 letters on ETDRS chart.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Patients receive the painless treatment while seated comfortably, and most sessions last an average of 30 minutes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dry AMD and Its Progression to Wet AMD<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Although all AMD patients start out with dry AMD, not all dry occurrences will progress to wet&nbsp; \u2013 approximately 90 per cent of AMD instances don\u2019t develop into wet AMD. The vascularization that sometimes occurs as a reaction to cells atrophying doesn\u2019t always occur. \u201cThe cells that are starving for more food produce this vascular endothelial growth factor, or VEGF, which is supposed to bring blood vessels toward them,\u201d he explains. \u201cIf they die before they\u2019re capable of doing this, then there\u2019s no production of the molecule to bring blood vessels, and therefore no progression to wet AMD.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Certain risk factors have been shown to increase the likelihood of patients developing wet AMD, while other factors may slow AMD\u2019s progression and prevent it from advancing to the wet form. Factors that increase the likelihood include progressing age, family history of AMD, smoking, eating an unhealthy diet, low levels of exercise and high blood pressure.<a href=\"https:\/\/macumira.com\/blog\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/#_ftn1\"><sup>[1]<\/sup><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To prevent or slow the progression to wet AMD, Dr. Rezende recommends smoking cessation, eating a well-balanced and nutritious diet, supplementing with lutein and wearing sunglasses with UVA\/UVB protection while outdoors, especially for light-skinned patients.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Screening is also an incredibly important tool. \u201cGo to the optometrist once a year,\u201d advises Dr. Rezende.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By managing the risk factors diligently, AMD patients can help prevent their disease from progressing to the more serious wet form.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Take control of your AMD with&nbsp;<a href=\"https:\/\/macumira.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">MacuMira Vision Therapy<\/a>&nbsp;<\/strong>and don\u2019t let AMD hold you back from enjoying life.&nbsp;<a href=\"https:\/\/macumira.com\/about\/\" target=\"_blank\" rel=\"noreferrer noopener\">MacuMira Vision Therapy<\/a>&nbsp;offers a non-invasive, effective, and comfortable solution to improve your vision and prevent progression.&nbsp;<a href=\"https:\/\/macumira.com\/find-a-physician\/\" target=\"_blank\" rel=\"noreferrer noopener\">Schedule a consultation today with a qualified physician<\/a>&nbsp;to explore your options for AMD treatment and learn how this innovative therapy can make a difference for you! If you have&nbsp;<a href=\"https:\/\/macumira.com\/patients-and-caregivers\/\" target=\"_blank\" rel=\"noreferrer noopener\">questions about AMD<\/a>&nbsp;or&nbsp;<a href=\"https:\/\/macumira.com\/eyecare-professionals\/\" target=\"_blank\" rel=\"noreferrer noopener\">MacuMira Vision Therapy as an eyecare professional<\/a>, don\u2019t hesitate to&nbsp;<a href=\"\/contact-us\" target=\"_blank\" rel=\"noopener\" title>contact us<\/a>&nbsp;for more information.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em><strong>Disclaimer<\/strong>: Always speak to your primary health care provider and\/or eye care provider before making any changes to your lifestyle, activities or diet.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">References<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\n<ol class=\"wp-block-list\">\n<li>&nbsp;<a href=\"https:\/\/www.aao.org\/eye-health\/diseases\/amd-macular-degeneration\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.aao.org\/eye-health\/diseases\/amd-macular-degeneration<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/opto.ca\/eye-health-library\/age-related-macular-degeneration-amd\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8330894\/#:~:text=The%20central%20most%20region%20of,photoreceptor%20cells%20and%20M%C3%BCller%20glia<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/opto.ca\/eye-health-library\/age-related-macular-degeneration-amd\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/opto.ca\/eye-health-library\/age-related-macular-degeneration-amd<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.aao.org\/eye-health\/diseases\/what-are-drusen\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.aao.org\/eye-health\/diseases\/what-are-drusen<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.seethepossibilities.ca\/eye-health\/age-related-macular-degeneration\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.seethepossibilities.ca\/eye-health\/age-related-macular-degeneration\/<\/a><\/li>\n<\/ol>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Good news for those with AMD: only about 10 per cent of cases progress from the less severe dry form to the more serious wet form, which poses greater risks to vision. Here\u2019s how to reduce your risk\u2026 How AMD affects the retina and macula Age-related macular degeneration (AMD)&nbsp;is a progressive eye disease wherein the [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/macumira.com\/ca\/age-related-macular-degeneration-amd-doesnt-always-progress-to-wet-amd\/\">Read More&#8230;<span class=\"screen-reader-text\"> from Age-related macular degeneration (AMD) doesn\u2019t always progress to wet AMD<\/span><\/a><\/p>\n","protected":false},"author":19,"featured_media":4594,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-4586","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Good news for those with AMD: only about 10 per cent of cases progress from the less severe dry form to the more serious wet form, which poses greater risks to vision. 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